Product Data Sheet

HD-800

Catalog No. A54936

main product photo
HD-800 is a potent tubulin inhibitor, exhibiting an IC50 of 4.3 nM and an EC50 for depolymerization of 24 nM. This compound is valuable for generating the radioactive tracer [11C]HD-800, which is capable of penetrating the blood-brain barrier. [11C]HD-800 serves as a useful tool for positron emission tomography (PET) applications in studying various neurological disorders.
Chemical Information
Catalog NumA54936
M. Wt269.30
FormulaC15H15N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1204408-27-4
Synonyms
SMILESN=1C=NC(=C2C1OC=C2C)N(C3=CC=C(OC)C=C3)C
Biological Activity
DescriptionHD-800 is a potent tubulin inhibitor, exhibiting an IC50 of 4.3 nM and an EC50 for depolymerization of 24 nM. This compound is valuable for generating the radioactive tracer [11C]HD-800, which is capable of penetrating the blood-brain barrier. [11C]HD-800 serves as a useful tool for positron emission tomography (PET) applications in studying various neurological disorders.
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