Product Data Sheet

Tubulin polymerization-IN-16

Catalog No. A54953

main product photo
Tubulin polymerization-IN-16 is a potent tubulin polymerization inhibitor designed to disrupt microtubule dynamics. This compound demonstrates significant anti-cancer activity with IC50 values ranging from 0.084 to 0.221 μM, effectively inducing cell cycle arrest at the G2/M phase in SGC-7901 cells. Its ability to inhibit tubulin polymerization makes it a valuable tool for research in cancer biology and therapeutic development.
Chemical Information
Catalog NumA54953
M. Wt465.50
FormulaC24H27N5O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2296731-38-7
Synonyms
SMILESCOC1=CC(C(C2=NN(N=C2N3CCN(CC3)C(C)=O)C4=CC=CC=C4)=O)=CC(OC)=C1OC
Biological Activity
DescriptionTubulin polymerization-IN-16 is a potent tubulin polymerization inhibitor designed to disrupt microtubule dynamics. This compound demonstrates significant anti-cancer activity with IC50 values ranging from 0.084 to 0.221 μM, effectively inducing cell cycle arrest at the G2/M phase in SGC-7901 cells. Its ability to inhibit tubulin polymerization makes it a valuable tool for research in cancer biology and therapeutic development.
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SHIPPING AND STORAGE
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