Product Data Sheet

N-Acetylcolchinol phosphate

Catalog No. A54955

main product photo
N-Acetylcolchinol phosphate is a potent inhibitor of tubulin polymerization. It binds to the tubulin cytoskeleton in the endothelial cells of tumor blood vessels, disrupting microtubule dynamics. This compound is valuable in anti-cancer research, providing insights into tumor vasculature and potential therapeutic strategies. Its application facilitates the study of tumor progression and vascularization in various cancer models.
Chemical Information
Catalog NumA54955
M. Wt437.38
FormulaC20H24NO8P
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.219923-05-4
SynonymsZD-6126; AZD-6126; ANG-453
SMILESO=P(OC1=CC=C(C2=C1)C3=C(C(OC)=C(C=C3CC[C@@H]2NC(C)=O)OC)OC)(O)O
Biological Activity
DescriptionN-Acetylcolchinol phosphate is a potent inhibitor of tubulin polymerization. It binds to the tubulin cytoskeleton in the endothelial cells of tumor blood vessels, disrupting microtubule dynamics. This compound is valuable in anti-cancer research, providing insights into tumor vasculature and potential therapeutic strategies. Its application facilitates the study of tumor progression and vascularization in various cancer models.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.