Product Data Sheet

Tubulin polymerization-IN-36

Catalog No. A54970

main product photo
Tubulin polymerization-IN-36 is a potent inhibitor of tubulin polymerization, exhibiting an IC50 of 2.8 μM. This compound selectively binds to the colchicine site of tubulin, thereby obstructing colchicine binding and disrupting microtubule formation. Tubulin polymerization-IN-36 is valuable for researching various cancers, including lymphomas, and provides insights into the mechanisms of tumorigenesis and cell division.
Chemical Information
Catalog NumA54970
M. Wt310.35
FormulaC18H18N2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2011784-91-9
Synonyms
SMILESCOC1=CC(CN2C=C3CCC4=C(C3=C2)ON=C4)=CC(OC)=C1
Biological Activity
DescriptionTubulin polymerization-IN-36 is a potent inhibitor of tubulin polymerization, exhibiting an IC50 of 2.8 μM. This compound selectively binds to the colchicine site of tubulin, thereby obstructing colchicine binding and disrupting microtubule formation. Tubulin polymerization-IN-36 is valuable for researching various cancers, including lymphomas, and provides insights into the mechanisms of tumorigenesis and cell division.
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