Product Data Sheet
Denibulin
Catalog No. A54972
Denibulin is a microtubule-tubulin inhibitor that reversibly disrupts microtubule assembly, affecting the cytoskeleton of tumor vascular endothelial cells. This novel vascular-disrupting agent exhibits tolerability and shows potential for anti-vascular effects, making it a candidate for further research in cancer therapy applications. Its mechanism offers insights into the modulation of tumor vasculature, supporting its exploration in studies of tumor growth and metastasis.
Chemical Information
| Catalog Num | A54972 |
|---|---|
| M. Wt | 385.44 |
| Formula | C18H19N5O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 284019-34-7 |
| Synonyms | MN-029 free base |
| SMILES | O=C(OC)NC1=NC2=CC(SC3=CC=C(NC([C@@H](N)C)=O)C=C3)=CC=C2N1 |
Biological Activity
| Description | Denibulin is a microtubule-tubulin inhibitor that reversibly disrupts microtubule assembly, affecting the cytoskeleton of tumor vascular endothelial cells. This novel vascular-disrupting agent exhibits tolerability and shows potential for anti-vascular effects, making it a candidate for further research in cancer therapy applications. Its mechanism offers insights into the modulation of tumor vasculature, supporting its exploration in studies of tumor growth and metastasis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
