Product Data Sheet
BMS 275183
Catalog No. A54974
BMS 275183 is a potent orally active analogue of Paclitaxel that targets microtubule stabilization. This compound exhibits significant antitumor activity in in vivo models, demonstrating efficacy against Paclitaxel-resistant tumors, including those with tubulin mutations or overexpressing P-glycoprotein. BMS 275183 is valuable for cancer research applications, particularly in studying non-small cell lung cancer (NSCLC) and prostate carcinoma.
Chemical Information
| Catalog Num | A54974 |
|---|---|
| M. Wt | 845.93 |
| Formula | C43H59NO16 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 355113-98-3 |
| Synonyms | |
| SMILES | COC(O[C@]12[C@@]([C@]3([C@@H](O)C[C@@]1([H])OC2)C)([H])[C@@H]([C@]4(C(C)(C([C@@H](OC(C)=O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C(C)(C)C)NC(OC(C)(C)C)=O)=O)C4)C)O)OC(C5=CC=CC=C5)=O)=O |
Biological Activity
| Description | BMS 275183 is a potent orally active analogue of Paclitaxel that targets microtubule stabilization. This compound exhibits significant antitumor activity in in vivo models, demonstrating efficacy against Paclitaxel-resistant tumors, including those with tubulin mutations or overexpressing P-glycoprotein. BMS 275183 is valuable for cancer research applications, particularly in studying non-small cell lung cancer (NSCLC) and prostate carcinoma. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
