Product Data Sheet
Tubulin polymerization-IN-90
Catalog No. A55009
Tubulin Polymerization-IN-90 is a selective inhibitor of tubulin polymerization, targeting the nocodazole-binding site on β-tubulin. By disrupting microtubule formation, it induces the release of extracellular vesicles marked by CD63 and promotes IL-8 secretion from cells. This compound has demonstrated reduced viability in various cancer cell lines and is particularly relevant for research applications in acute T-lymphoblastic leukemia and other malignancies characterized by aberrant tubulin dynamics.
Chemical Information
| Catalog Num | A55009 |
|---|---|
| M. Wt | 354.43 |
| Formula | C21H14N4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3006800-41-2 |
| Synonyms | |
| SMILES | C1(C=CC=C2)=C2C=CC=C1C3=CN(N=N3)C4=CC(C5=CC=CS5)=CN=C4 |
Biological Activity
| Description | Tubulin Polymerization-IN-90 is a selective inhibitor of tubulin polymerization, targeting the nocodazole-binding site on β-tubulin. By disrupting microtubule formation, it induces the release of extracellular vesicles marked by CD63 and promotes IL-8 secretion from cells. This compound has demonstrated reduced viability in various cancer cell lines and is particularly relevant for research applications in acute T-lymphoblastic leukemia and other malignancies characterized by aberrant tubulin dynamics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
