Product Data Sheet
Anticancer agent 139
Catalog No. A55016
Anticancer agent 139 (Compound 6h) primarily targets tubulin through π-cationic interactions with the lysine residue Lys352, demonstrating strong anticancer activity. This compound exhibits significant efficacy against various cancer cell lines, including SNB-19, OVCAR-8, and NCI-H40, with proliferation growth inhibition (PGI) values of 86.61, 85.26, and 75.99, respectively. Additionally, anticancer agent 139 shows moderate activity against HOP-62, SNB-75, and others, making it a valuable tool for cancer research and drug discovery applications.
Chemical Information
| Catalog Num | A55016 |
|---|---|
| M. Wt | 319.28 |
| Formula | C16H12F3N3O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2954795-29-8 |
| Synonyms | |
| SMILES | CC1=CC(C)=C(C=C1)NC2=NN=C(O2)C3=CC(F)=C(C(F)=C3)F |
Biological Activity
| Description | Anticancer agent 139 (Compound 6h) primarily targets tubulin through π-cationic interactions with the lysine residue Lys352, demonstrating strong anticancer activity. This compound exhibits significant efficacy against various cancer cell lines, including SNB-19, OVCAR-8, and NCI-H40, with proliferation growth inhibition (PGI) values of 86.61, 85.26, and 75.99, respectively. Additionally, anticancer agent 139 shows moderate activity against HOP-62, SNB-75, and others, making it a valuable tool for cancer research and drug discovery applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
