Product Data Sheet
7a-Hydroxyfrullanolide
Catalog No. A55019
7a-Hydroxyfrullanolide is an eudesmanolide sesquiterpene lactone that primarily targets β-tubulin, inhibiting its polymerization along with α-tubulin. This compound exhibits significant anticancer properties by triggering a DNA damage response that leads to cell cycle arrest in the G2/M phase. Its potential applications in cancer research make it a valuable tool for exploring microtubule dynamics and therapeutic strategies in oncology. Isolated from members of the Asteraceae family, 7a-Hydroxyfrullanolide offers insights into natural product-based anticancer mechanisms.
Chemical Information
| Catalog Num | A55019 |
|---|---|
| M. Wt | 248.32 |
| Formula | C15H20O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 105578-87-8 |
| Synonyms | |
| SMILES | O[C@]12[C@](OC(C2=C)=O)([H])C3=C(C)CCC[C@@]3(CC1)C |
Biological Activity
| Description | 7a-Hydroxyfrullanolide is an eudesmanolide sesquiterpene lactone that primarily targets β-tubulin, inhibiting its polymerization along with α-tubulin. This compound exhibits significant anticancer properties by triggering a DNA damage response that leads to cell cycle arrest in the G2/M phase. Its potential applications in cancer research make it a valuable tool for exploring microtubule dynamics and therapeutic strategies in oncology. Isolated from members of the Asteraceae family, 7a-Hydroxyfrullanolide offers insights into natural product-based anticancer mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
