Product Data Sheet
N-Deacetylcolchicine
Catalog No. A55057
N-Deacetylcolchicine is a potent inhibitor of microtubule polymerization, exhibiting an IC50 of 3 μM against bovine brain microtubules. As a derivative of colchicine, it effectively activates the GTPase activity of microtubules, making it valuable for research related to cancer biology and treatment mechanisms. This compound offers significant potential for studies focusing on microtubule dynamics and their role in cancer cell proliferation.
Chemical Information
| Catalog Num | A55057 |
|---|---|
| M. Wt | 357.40 |
| Formula | C20H23NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3476-50-4 |
| Synonyms | |
| SMILES | COC1=C2C(C([C@H](CCC2=CC(OC)=C1OC)N)=C3)=CC=C(OC)C3=O |
Biological Activity
| Description | N-Deacetylcolchicine is a potent inhibitor of microtubule polymerization, exhibiting an IC50 of 3 μM against bovine brain microtubules. As a derivative of colchicine, it effectively activates the GTPase activity of microtubules, making it valuable for research related to cancer biology and treatment mechanisms. This compound offers significant potential for studies focusing on microtubule dynamics and their role in cancer cell proliferation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
