Product Data Sheet
ST045945
Catalog No. A55058
ST045945 is a selective inhibitor of serine/threonine kinases, specifically targeting CHK1 and CHK2 pathways that regulate cell cycle checkpoints. This compound effectively induces G2/M phase arrest in tumor cells, leading to DNA damage and inhibition of cell proliferation. ST045945 is utilized in cancer research to explore therapeutic strategies by disrupting critical signaling pathways associated with tumor progression and resistance to chemotherapy.
Chemical Information
| Catalog Num | A55058 |
|---|---|
| M. Wt | 308.35 |
| Formula | C17H12N2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 93326-70-6 |
| Synonyms | |
| SMILES | O=S(C1=CC=CC2=C1C=CC=C2)(N3C=NC4=C3C=CC=C4)=O |
Biological Activity
| Description | ST045945 is a selective inhibitor of serine/threonine kinases, specifically targeting CHK1 and CHK2 pathways that regulate cell cycle checkpoints. This compound effectively induces G2/M phase arrest in tumor cells, leading to DNA damage and inhibition of cell proliferation. ST045945 is utilized in cancer research to explore therapeutic strategies by disrupting critical signaling pathways associated with tumor progression and resistance to chemotherapy. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
