Product Data Sheet
Mps1-IN-7
Catalog No. A55063
Mps1-IN-7 is a potent inhibitor of MPS1 with an IC50 value of 0.020 μM, demonstrating selectivity over JNK1 and JNK2 (IC50 values of 0.11 μM and 0.22 μM, respectively). This compound exhibits significant antiproliferative effects across various cancer cell lines, including SW620, CAL51, Miapaca-2, and RMG1, with GI50 values of 0.065, 0.068, 0.25, and 0.110 μM, respectively. Mps1-IN-7 can be utilized in research focused on cell cycle regulation and the development of targeted cancer therapies.
Chemical Information
| Catalog Num | A55063 |
|---|---|
| M. Wt | 431.53 |
| Formula | C24H29N7O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1578244-34-4 |
| Synonyms | |
| SMILES | CC(C)(C)[C@@H](NC1=NC=CC2=CN=C(NC3=CC=C(C4=CN(C)N=C4)C=C3OC)N=C21)C |
Biological Activity
| Description | Mps1-IN-7 is a potent inhibitor of MPS1 with an IC50 value of 0.020 μM, demonstrating selectivity over JNK1 and JNK2 (IC50 values of 0.11 μM and 0.22 μM, respectively). This compound exhibits significant antiproliferative effects across various cancer cell lines, including SW620, CAL51, Miapaca-2, and RMG1, with GI50 values of 0.065, 0.068, 0.25, and 0.110 μM, respectively. Mps1-IN-7 can be utilized in research focused on cell cycle regulation and the development of targeted cancer therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
