Product Data Sheet
Mps1-IN-10
Catalog No. A55066
Mps1-IN-10 is a potent inhibitor of Mps1, exhibiting an IC50 of 6.4 nM. This compound effectively suppresses the proliferation of cancer cells, demonstrated by a GI50 of 11 nM in the MDA-MB-231 cell line. Mps1-IN-10 also shows significant anti-tumor efficacy in preclinical models using MDA-MB-231 xenografts, making it a valuable tool for cancer research applications focused on cell cycle regulation and tumor growth inhibition.
Chemical Information
| Catalog Num | A55066 |
|---|---|
| M. Wt | 445.52 |
| Formula | C24H27N7O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2489220-49-5 |
| Synonyms | |
| SMILES | N#CC1=CNC2=NC(NC3=CC=C(N4C(CCC4)=O)C=C3OC)=NC(NC5CCCCC5)=C21 |
Biological Activity
| Description | Mps1-IN-10 is a potent inhibitor of Mps1, exhibiting an IC50 of 6.4 nM. This compound effectively suppresses the proliferation of cancer cells, demonstrated by a GI50 of 11 nM in the MDA-MB-231 cell line. Mps1-IN-10 also shows significant anti-tumor efficacy in preclinical models using MDA-MB-231 xenografts, making it a valuable tool for cancer research applications focused on cell cycle regulation and tumor growth inhibition. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
