Product Data Sheet

TTK inhibitor 3

Catalog No. A55067

main product photo
TTK Inhibitor 3 is a highly potent and selective inhibitor of TTK, a critical enzyme involved in the spindle assembly checkpoint. With an IC50 value of 3.0 nM, this compound effectively disrupts TTK activity, making it a valuable tool for studying cell cycle regulation and mitotic progression. Its application extends to research focused on cancer biology, particularly in the context of therapeutic approaches targeting aberrant cell division.
Chemical Information
Catalog NumA55067
M. Wt727.90
FormulaC42H49N9O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2820453-41-4
Synonyms
SMILESO=C1C2=CC(C3=C4C(NC=C4)=NC(NC5=CC=C(N6CCC(C(N7CC8(CN(C)C8)C7)=O)CC6)C=C5OC)=N3)=CN2CCN1C9=C(CC)C=CC=C9CC
Biological Activity
DescriptionTTK Inhibitor 3 is a highly potent and selective inhibitor of TTK, a critical enzyme involved in the spindle assembly checkpoint. With an IC50 value of 3.0 nM, this compound effectively disrupts TTK activity, making it a valuable tool for studying cell cycle regulation and mitotic progression. Its application extends to research focused on cancer biology, particularly in the context of therapeutic approaches targeting aberrant cell division.
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SHIPPING AND STORAGE
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