Product Data Sheet
N-6-Methyl-2-deoxyadenosine
Catalog No. A55097
N-6-Methyl-2-deoxyadenosine (m6dA) is an adenine nucleoside analogue that targets nuclear processes and DNA replication machinery. It functions as a multifaceted epigenetic regulator, influencing transcription, DNA damage response, cell cycle progression, transposon silencing, and nucleosome organization in both prokaryotic and eukaryotic systems. Additionally, m6dA plays a crucial role in mitochondrial epigenetic inheritance and is implicated in fear extinction memory in murine models. Dysregulated levels of N-6-Methyl-2-deoxyadenosine have been associated with various cancers, making it a valuable reagent for research into glioblastoma, triple-negative breast cancer, and conditioned fear responses.
Chemical Information
| Catalog Num | A55097 |
|---|---|
| M. Wt | 265.27 |
| Formula | C11H15N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2002-35-9 |
| Synonyms | m6dA |
| SMILES | OC[C@@H]1[C@@H](O)C[C@H](N2C(N=CN=C3NC)=C3N=C2)O1 |
Biological Activity
| Description | N-6-Methyl-2-deoxyadenosine (m6dA) is an adenine nucleoside analogue that targets nuclear processes and DNA replication machinery. It functions as a multifaceted epigenetic regulator, influencing transcription, DNA damage response, cell cycle progression, transposon silencing, and nucleosome organization in both prokaryotic and eukaryotic systems. Additionally, m6dA plays a crucial role in mitochondrial epigenetic inheritance and is implicated in fear extinction memory in murine models. Dysregulated levels of N-6-Methyl-2-deoxyadenosine have been associated with various cancers, making it a valuable reagent for research into glioblastoma, triple-negative breast cancer, and conditioned fear responses. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
