Product Data Sheet
5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)
Catalog No. A55131
5'-ODMT cEt N-Bzm5 C Phosphoramidite is a modified nucleic acid analog that effectively enhances antisense oligonucleotide performance. Through the incorporation of a cEt modification, this reagent promotes the formation of a specific conformation of the furanose ring, which significantly improves hybridization to complementary RNA. Its primary applications include research into gene expression regulation associated with metabolic disorders, cardiovascular diseases, and cancer, as well as the advancement of antisense therapeutic compounds.
Chemical Information
| Catalog Num | A55131 |
|---|---|
| M. Wt | 889.97 |
| Formula | C49H56N5O9P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1197033-17-2 |
| Synonyms | |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]([C@](O[C@H]1C)([H])[C@H](N2C(N=C(C(C)=C2)NC(C3=CC=CC=C3)=O)=O)O4)[C@@]41COC(C5=CC=C(C=C5)OC)(C6=CC=CC=C6)C7=CC=C(C=C7)OC |
Biological Activity
| Description | 5'-ODMT cEt N-Bzm5 C Phosphoramidite is a modified nucleic acid analog that effectively enhances antisense oligonucleotide performance. Through the incorporation of a cEt modification, this reagent promotes the formation of a specific conformation of the furanose ring, which significantly improves hybridization to complementary RNA. Its primary applications include research into gene expression regulation associated with metabolic disorders, cardiovascular diseases, and cancer, as well as the advancement of antisense therapeutic compounds. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
