Product Data Sheet
Orotic acid zinc
Catalog No. A55189
Orotic acid zinc acts as an active compound involved in the biosynthesis of pyrimidine nucleotides and RNA. It is released as a product from mitochondrial dihydroorotate dehydrogenase (DHODH) and subsequently converted to UMP by UMP synthase in the cytoplasm. This compound is utilized as a biomarker in newborn screening for urea cycle disorders and has been shown to induce hepatic steatosis and hepatomegaly in rodent models, making it relevant for studies in metabolic and liver disorders.
Chemical Information
| Catalog Num | A55189 |
|---|---|
| M. Wt | 188.79 |
| Formula | C5H4N2O4Zn0.5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 68399-76-8 |
| Synonyms | 6-Carboxyuracil zinc; Vitamin B13 zinc |
| SMILES | O=C(C(NC1=O)=CC(N1)=O)O.[0.5Zn] |
Biological Activity
| Description | Orotic acid zinc acts as an active compound involved in the biosynthesis of pyrimidine nucleotides and RNA. It is released as a product from mitochondrial dihydroorotate dehydrogenase (DHODH) and subsequently converted to UMP by UMP synthase in the cytoplasm. This compound is utilized as a biomarker in newborn screening for urea cycle disorders and has been shown to induce hepatic steatosis and hepatomegaly in rodent models, making it relevant for studies in metabolic and liver disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
