Product Data Sheet

DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite

Catalog No. A55227

main product photo
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite functions as a phosphoramidite derivative of 5-fluoro-2'-deoxycytidine, specifically designed for use in solid-phase oligonucleotide synthesis. This reagent enables the incorporation of the nucleoside analogue into DNA sequences, facilitating studies of nucleotide metabolism, DNA repair mechanisms, and the effects of fluorinated nucleotides on enzyme activity. Its chemical structure allows for efficient coupling and enhances the stability of synthesized oligonucleotides, contributing to a range of molecular biology applications.
Chemical Information
Catalog NumA55227
M. Wt747.79
FormulaC39H47FN5O7P
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.143774-48-5
Synonyms
SMILESO=C(N=C(N)C(F)=C1)N1[C@@H]2O[C@H](COC(C3=CC=C(OC)C=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C2
Biological Activity
DescriptionDMTr-5-fluoro-2'-deoxycytidine-phosphoramidite functions as a phosphoramidite derivative of 5-fluoro-2'-deoxycytidine, specifically designed for use in solid-phase oligonucleotide synthesis. This reagent enables the incorporation of the nucleoside analogue into DNA sequences, facilitating studies of nucleotide metabolism, DNA repair mechanisms, and the effects of fluorinated nucleotides on enzyme activity. Its chemical structure allows for efficient coupling and enhances the stability of synthesized oligonucleotides, contributing to a range of molecular biology applications.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.