Product Data Sheet
Ultevursen
Catalog No. A55240
Ultevursen (QR-421a) is a single-stranded RNA oligonucleotide that acts as a splice-switching agent, designed to promote the skipping of exon 13 in the USH2A gene, which encodes usherin. This mechanism aims to halt vision loss associated with retinitis pigmentosa caused by mutations within this exon. Ultevursen has potential applications in gene therapy and research focused on treatments for genetic retinal diseases.
Chemical Information
| Catalog Num | A55240 |
|---|---|
| M. Wt | 8372.24 |
| Formula | C273H391N81O144P20S20 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2642382-41-8 |
| Synonyms | QR-421a |
| SMILES | [Ultevursen] |
Biological Activity
| Description | Ultevursen (QR-421a) is a single-stranded RNA oligonucleotide that acts as a splice-switching agent, designed to promote the skipping of exon 13 in the USH2A gene, which encodes usherin. This mechanism aims to halt vision loss associated with retinitis pigmentosa caused by mutations within this exon. Ultevursen has potential applications in gene therapy and research focused on treatments for genetic retinal diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
