Product Data Sheet
2-Chloro-2'-deoxy-6-O-methylinosine
Catalog No. A55478
2-Chloro-2'-deoxy-6-O-methylinosine is a hypoxanthine analog that serves as a potent modulator of various biological pathways. This compound exhibits significant anti-inflammatory properties and functions as a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor, providing cytoprotection by inhibiting PARP activity and mitigating peroxynitrite-induced mitochondrial depolarization and superoxide production. Additionally, this analog can be utilized as an indicator of hypoxia in research settings, making it valuable for studies related to cellular response under low oxygen conditions.
Chemical Information
| Catalog Num | A55478 |
|---|---|
| M. Wt | 300.70 |
| Formula | C11H13ClN4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 146196-07-8 |
| Synonyms | |
| SMILES | O[C@@H]1[C@@H](CO)O[C@H](C1)N(C=N2)C3=C2C(OC)=NC(Cl)=N3 |
Biological Activity
| Description | 2-Chloro-2'-deoxy-6-O-methylinosine is a hypoxanthine analog that serves as a potent modulator of various biological pathways. This compound exhibits significant anti-inflammatory properties and functions as a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor, providing cytoprotection by inhibiting PARP activity and mitigating peroxynitrite-induced mitochondrial depolarization and superoxide production. Additionally, this analog can be utilized as an indicator of hypoxia in research settings, making it valuable for studies related to cellular response under low oxygen conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
