Product Data Sheet

AFB1-FapyGua

Catalog No. A55759

main product photo
AFB1-FapyGua is a prominent guanine adduct formed from the alkylation of nucleic acids by aflatoxin B1 (AFB1). This compound has been shown to exert significant mutagenic effects, making it crucial for studying DNA damage and repair mechanisms. AFB1-FapyGua serves as an important tool in cancer research, particularly in understanding the cellular response to genotoxic stress and the mutational processes involved in tumorigenesis.
Chemical Information
Catalog NumA55759
M. Wt497.41
FormulaC22H19N5O9
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.65386-83-6
Synonyms
SMILESO[C@@H]1[C@@]2([H])C3=C(O[C@@]2([H])O[C@H]1N(C4=C(NC(N)=NC4=O)N)C=O)C=C(OC)C(C5=C6C(CC5)=O)=C3OC6=O
Biological Activity
DescriptionAFB1-FapyGua is a prominent guanine adduct formed from the alkylation of nucleic acids by aflatoxin B1 (AFB1). This compound has been shown to exert significant mutagenic effects, making it crucial for studying DNA damage and repair mechanisms. AFB1-FapyGua serves as an important tool in cancer research, particularly in understanding the cellular response to genotoxic stress and the mutational processes involved in tumorigenesis.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.