Product Data Sheet

N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine

Catalog No. A56118

main product photo
N2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an alkyne moiety that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it a versatile tool for chemical biology applications.
Chemical Information
Catalog NumA56118
M. Wt497.50
FormulaC24H27N5O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2095417-23-3
Synonyms
SMILESOC[C@@H]1[C@@H](O)[C@@H](OCC#C)[C@H](N2C(NC(NC(COC3=CC=C(C(C)C)C=C3)=O)=NC4=O)=C4N=C2)O1
Biological Activity
DescriptionN2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an alkyne moiety that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it a versatile tool for chemical biology applications.
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