Flurocitabine
Catalog No. A56252

Flurocitabine, a fluorinated analog of cytosine arabinoside, acts as an antineoplastic agent by undergoing partial hydrolysis in vivo to produce two active metabolites: arabinosyl-fluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU). This compound demonstrates significant antitumor activity and has shown promise in phase I clinical studies for acute leukemia and various solid tumors. Its unique mechanism of action makes Flurocitabine a valuable tool for cancer research and therapy development.
Chemical Information
| Catalog Num | A56252 |
|---|---|
| M. Wt | 243.19 |
| Formula | C9H10FN3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 37717-21-8 |
| Synonyms | 5-Fluorocyclocytidine; 5'-Fluorocyclocytidine |
| SMILES | O[C@H]1[C@@]2([H])[C@](O[C@@H]1CO)([H])N3C(O2)=NC(C(F)=C3)=N |
Biological Activity
| Description | Flurocitabine, a fluorinated analog of cytosine arabinoside, acts as an antineoplastic agent by undergoing partial hydrolysis in vivo to produce two active metabolites: arabinosyl-fluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU). This compound demonstrates significant antitumor activity and has shown promise in phase I clinical studies for acute leukemia and various solid tumors. Its unique mechanism of action makes Flurocitabine a valuable tool for cancer research and therapy development. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


