Product Data Sheet

3’-Azido-3’-deoxycytidine

Catalog No. A56268

main product photo
3’-Azido-3’-deoxycytidine is a purine nucleoside analog that exhibits notable antitumor activity, primarily targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it valuable in diverse chemical biology applications.
Chemical Information
Catalog NumA56268
M. Wt268.23
FormulaC9H12N6O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.70580-87-9
Synonyms
SMILESOC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N2C(N=C(C=C2)N)=O)O1
Biological Activity
Description3’-Azido-3’-deoxycytidine is a purine nucleoside analog that exhibits notable antitumor activity, primarily targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it valuable in diverse chemical biology applications.
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SHIPPING AND STORAGE
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