Product Data Sheet
5′-Azido-2′,5′-dideoxyadenosine
Catalog No. A56358
5′-Azido-2′,5′-dideoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity by targeting indolent lymphoid malignancies. Its primary mechanisms include inhibition of DNA synthesis and induction of apoptosis. This compound is also a valuable click chemistry reagent, featuring an azide group that allows for copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring DBCO or BCN groups, making it suitable for various biochemical applications.
Chemical Information
| Catalog Num | A56358 |
|---|---|
| M. Wt | 276.25 |
| Formula | C10H12N8O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 42204-43-3 |
| Synonyms | |
| SMILES | O[C@@H]1[C@@H](CN=[N+]=[N-])O[C@@H](N2C(N=CN=C3N)=C3N=C2)C1 |
Biological Activity
| Description | 5′-Azido-2′,5′-dideoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity by targeting indolent lymphoid malignancies. Its primary mechanisms include inhibition of DNA synthesis and induction of apoptosis. This compound is also a valuable click chemistry reagent, featuring an azide group that allows for copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring DBCO or BCN groups, making it suitable for various biochemical applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
