Product Data Sheet

PLK4-IN-1

Catalog No. A56893

main product photo
PLK4-IN-1 is a selective inhibitor of PLK4, exhibiting an IC50 of less than or equal to 0.1 μM. This compound plays a critical role in cell cycle regulation through the inhibition of polo-like kinase 4 activity. Its application is significant in research focusing on cell proliferation, cancer therapeutics, and understanding mitotic processes.
Chemical Information
Catalog NumA56893
M. Wt431.23
FormulaC18H14IN3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1247001-12-2
Synonyms
SMILESO=C([C@@]12[C@H](C3=CC4=C(C=C3)C(I)=NN4)C1)NC5=C2C=C(OC)C=C5.[Relative stereochemistry]
Biological Activity
DescriptionPLK4-IN-1 is a selective inhibitor of PLK4, exhibiting an IC50 of less than or equal to 0.1 μM. This compound plays a critical role in cell cycle regulation through the inhibition of polo-like kinase 4 activity. Its application is significant in research focusing on cell proliferation, cancer therapeutics, and understanding mitotic processes.
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SHIPPING AND STORAGE
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