Product Data Sheet

CHIC35

Catalog No. A56994

main product photo
CHIC35 is a selective inhibitor of SIRT1, exhibiting an IC50 of 0.124 μM. It demonstrates preferential inhibition of SIRT1 over SIRT2 (IC50=2.8 μM) and SIRT3 (IC50>100 μM). This compound is recognized for its anti-inflammatory properties and is applicable in research related to CHARGE syndrome.
Chemical Information
Catalog NumA56994
M. Wt262.73
FormulaC14H15ClN2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.848193-72-6
Synonyms
SMILESO=C([C@H]1CCCCC2=C1NC3=C2C=C(Cl)C=C3)N
Biological Activity
DescriptionCHIC35 is a selective inhibitor of SIRT1, exhibiting an IC50 of 0.124 μM. It demonstrates preferential inhibition of SIRT1 over SIRT2 (IC50=2.8 μM) and SIRT3 (IC50>100 μM). This compound is recognized for its anti-inflammatory properties and is applicable in research related to CHARGE syndrome.
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