Product Data Sheet
F0911-7667
Catalog No. A56996
F0911-7667 is a potent activator of SIRT1, promoting autophagic cell death in U87MG and T98G glioblastoma cells through the activation of the AMPK-mTOR-ULK complex. Additionally, this compound has demonstrated its ability to reduce p53 acetylation in IMR32 neuroblastoma cells, providing protective effects against cell death induced by amyloid-beta (Aβ) fragments. Its unique mechanism and biological activities make it valuable for research in cancer and neurodegenerative disease models.
Chemical Information
| Catalog Num | A56996 |
|---|---|
| M. Wt | 535.04 |
| Formula | C26H19ClN4O3S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 361198-09-6 |
| Synonyms | |
| SMILES | O=C1N(C2=NC3=CC=CC=C3S2)N=C(CSC4=CC=C(Cl)C=C4)/C1=C\NCC5=CC=C(OCO6)C6=C5 |
Biological Activity
| Description | F0911-7667 is a potent activator of SIRT1, promoting autophagic cell death in U87MG and T98G glioblastoma cells through the activation of the AMPK-mTOR-ULK complex. Additionally, this compound has demonstrated its ability to reduce p53 acetylation in IMR32 neuroblastoma cells, providing protective effects against cell death induced by amyloid-beta (Aβ) fragments. Its unique mechanism and biological activities make it valuable for research in cancer and neurodegenerative disease models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
