Product Data Sheet
Guttiferone G
Catalog No. A57007
Guttiferone G is a selective inhibitor of the human SIRT1 and SIRT2 deacetylases, exhibiting IC50 values of 9 μM and 22 μM, respectively. This compound demonstrates weak cytotoxicity in the A2780 human ovarian cancer cell line, with an IC50 of 8.0 μg/mL. Guttiferone G is derived from Garcinia macrophylla and may serve as a valuable tool in research studies exploring SIRT1 and SIRT2 modulation in cellular processes.
Chemical Information
| Catalog Num | A57007 |
|---|---|
| M. Wt | 670.92 |
| Formula | C43H58O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 666174-75-0 |
| Synonyms | |
| SMILES | C/C(C)=C/C[C@](C([C@]12C/C=C(C)/C)=O)(C(C(C(C(C=C3)=CC(O)=C3O)=O)=C1O)=O)[C@](C)([C@@H](C2)C/C=C(C)/CC/C=C(C)/C)CC/C=C(C)/C |
Biological Activity
| Description | Guttiferone G is a selective inhibitor of the human SIRT1 and SIRT2 deacetylases, exhibiting IC50 values of 9 μM and 22 μM, respectively. This compound demonstrates weak cytotoxicity in the A2780 human ovarian cancer cell line, with an IC50 of 8.0 μg/mL. Guttiferone G is derived from Garcinia macrophylla and may serve as a valuable tool in research studies exploring SIRT1 and SIRT2 modulation in cellular processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
