Product Data Sheet
AGK7
Catalog No. A57013
AGK7 is a selective inhibitor of sirtuin 2 (SIRT2), demonstrating significant neuroprotective effects in the context of Parkinson's disease. This compound has been shown to alleviate alpha-synuclein toxicity and improve inclusion morphology in cellular models. In addition, AGK7 effectively protects against dopaminergic cell death in both in vitro studies and Drosophila models, making it a valuable tool for researching neurodegenerative disorders.
Chemical Information
| Catalog Num | A57013 |
|---|---|
| M. Wt | 434.27 |
| Formula | C23H13Cl2N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 304896-21-7 |
| Synonyms | SIRT2 Inhibitor,Inactive Control |
| SMILES | O=C(NC1=CC=CC2=C1N=CC=C2)/C(C#N)=C/C3=CC=C(O3)C4=CC(Cl)=CC=C4Cl |
Biological Activity
| Description | AGK7 is a selective inhibitor of sirtuin 2 (SIRT2), demonstrating significant neuroprotective effects in the context of Parkinson's disease. This compound has been shown to alleviate alpha-synuclein toxicity and improve inclusion morphology in cellular models. In addition, AGK7 effectively protects against dopaminergic cell death in both in vitro studies and Drosophila models, making it a valuable tool for researching neurodegenerative disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
