Product Data Sheet
Elomotecan hydrochloride
Catalog No. A57109
Elomotecan hydrochloride is a potent inhibitor of topoisomerases I and II, classified as a camptothecin analog from the homocamptothecin family. This compound demonstrates significant anti-proliferative activity in various tumor cell lines, surpassing the effectiveness of other known anticancer agents targeting these topoisomerases. Its mechanism of action makes Elomotecan hydrochloride a valuable tool in cancer research, particularly in studies focusing on DNA damage response and cell cycle regulation.
Chemical Information
| Catalog Num | A57109 |
|---|---|
| M. Wt | 558.50 |
| Formula | C29H33Cl2N3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 220997-99-9 |
| Synonyms | BN 80927 |
| SMILES | O=C(OC1)C[C@](O)(CC)C2=C1C(N3CC4=C(CN5CCC(C)CC5)C6=CC(C)=C(Cl)C=C6N=C4C3=C2)=O.[H]Cl |
Biological Activity
| Description | Elomotecan hydrochloride is a potent inhibitor of topoisomerases I and II, classified as a camptothecin analog from the homocamptothecin family. This compound demonstrates significant anti-proliferative activity in various tumor cell lines, surpassing the effectiveness of other known anticancer agents targeting these topoisomerases. Its mechanism of action makes Elomotecan hydrochloride a valuable tool in cancer research, particularly in studies focusing on DNA damage response and cell cycle regulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
