Product Data Sheet
Elinafide
Catalog No. A57117
Elinafide is an anticancer agent featuring a naphthalimide structure that targets DNA. It disrupts cellular metabolism by inserting a planar ring into the DNA double helix, leading to interactions with topoisomerase II enzymes. This mechanism results in significant cytotoxicity, with an IC50 value of 0.014 μM observed in HT-29 colorectal cancer cells. Elinafide is applicable for research on DNA-binding compounds and their therapeutic potential in oncology.
Chemical Information
| Catalog Num | A57117 |
|---|---|
| M. Wt | 520.58 |
| Formula | C31H28N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 162706-37-8 |
| Synonyms | LU 79553 |
| SMILES | O=C1N(CCNCCCNCCN(C(C2=CC=CC3=CC=CC4=C23)=O)C4=O)C(C5=CC=CC6=CC=CC1=C56)=O |
Biological Activity
| Description | Elinafide is an anticancer agent featuring a naphthalimide structure that targets DNA. It disrupts cellular metabolism by inserting a planar ring into the DNA double helix, leading to interactions with topoisomerase II enzymes. This mechanism results in significant cytotoxicity, with an IC50 value of 0.014 μM observed in HT-29 colorectal cancer cells. Elinafide is applicable for research on DNA-binding compounds and their therapeutic potential in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
