Product Data Sheet
CH-0793076 TFA
Catalog No. A57122
CH-0793076 TFA is a hexacyclic camptothecin analog that functions as a potent inhibitor of DNA topoisomerase I, exhibiting an IC50 value of 2.3 μM. This compound demonstrates significant efficacy against tumor cells expressing the breast cancer resistance protein (BCRP). CH-0793076 TFA is primarily utilized in cancer research, particularly for studies focused on overcoming drug resistance in breast cancer and other malignancies where topoisomerase I plays a critical role.
Chemical Information
| Catalog Num | A57122 |
|---|---|
| M. Wt | 572.53 |
| Formula | C28H27F3N4O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2740278-76-4 |
| Synonyms | TP3076 TFA |
| SMILES | O=C1[C@](O)(CC)C(C=C23)=C(CO1)C(N2CC(C3=N4)=C5N(CCCCC)C=NC6=C5C4=CC=C6)=O.O=C(O)C(F)(F)F |
Biological Activity
| Description | CH-0793076 TFA is a hexacyclic camptothecin analog that functions as a potent inhibitor of DNA topoisomerase I, exhibiting an IC50 value of 2.3 μM. This compound demonstrates significant efficacy against tumor cells expressing the breast cancer resistance protein (BCRP). CH-0793076 TFA is primarily utilized in cancer research, particularly for studies focused on overcoming drug resistance in breast cancer and other malignancies where topoisomerase I plays a critical role. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
