Product Data Sheet
TOP3B-IN-1
Catalog No. A57136
TOP3B-IN-1 is a selective inhibitor of Topoisomerase IIIβ (TOP3B), disrupting the formation of TOP3B cleavage complexes (TOP3Bccs) with DNA and RNA. This compound destabilizes existing TOP3Bccs, making it valuable for investigating the role of TOP3B in cellular processes. TOP3B-IN-1 serves as a useful control in the development of new TOP3B-targeting inhibitors, allowing for enhanced understanding of this enzyme’s function in biological systems.
Chemical Information
| Catalog Num | A57136 |
|---|---|
| M. Wt | 530.66 |
| Formula | C34H34N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 67047-17-0 |
| Synonyms | |
| SMILES | COC1=CC2=NC3=C(C=CC=C3)C(NCCCCCCNC4=C5C=CC(OC)=CC5=NC6=C4C=CC=C6)=C2C=C1 |
Biological Activity
| Description | TOP3B-IN-1 is a selective inhibitor of Topoisomerase IIIβ (TOP3B), disrupting the formation of TOP3B cleavage complexes (TOP3Bccs) with DNA and RNA. This compound destabilizes existing TOP3Bccs, making it valuable for investigating the role of TOP3B in cellular processes. TOP3B-IN-1 serves as a useful control in the development of new TOP3B-targeting inhibitors, allowing for enhanced understanding of this enzyme’s function in biological systems. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
