Product Data Sheet

Pixantrone hydrochloride

Catalog No. A57150

main product photo
Pixantrone hydrochloride is a topoisomerase II inhibitor that functions through DNA intercalation, exhibiting significant anti-tumor activity. It is a structural analog of mitoxantrone and has shown promise in preclinical and clinical studies for treating various malignancies. This compound is valuable for research applications in cancer biology, particularly in studies focused on the mechanisms of DNA damage and repair, as well as the assessment of therapeutic efficacy in oncology.
Chemical Information
Catalog NumA57150
M. Wt361.83
FormulaC17H20ClN5O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.175989-38-5
SynonymsBBR 2778 hydrochloride
SMILESO=C(C1=C(NCCN)C=CC(NCCN)=C12)C3=C(C=NC=C3)C2=O.Cl
Biological Activity
DescriptionPixantrone hydrochloride is a topoisomerase II inhibitor that functions through DNA intercalation, exhibiting significant anti-tumor activity. It is a structural analog of mitoxantrone and has shown promise in preclinical and clinical studies for treating various malignancies. This compound is valuable for research applications in cancer biology, particularly in studies focused on the mechanisms of DNA damage and repair, as well as the assessment of therapeutic efficacy in oncology.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.