Product Data Sheet
Topoisomerase II inhibitor 6
Catalog No. A57161
Topoisomerase II inhibitor 6 is a potent and selective inhibitor of topoisomerase II, derived from tryptanthrin. This compound demonstrates significant antiproliferative activity across various tumor cell lines and effectively halts the cell cycle of CCRF-CEM cells at the G2 phase, while inducing DNA double-strand breaks (DSBs). Its robust mechanism of action makes Topoisomerase II inhibitor 6 a valuable reagent for cancer research and therapeutic investigations.
Chemical Information
| Catalog Num | A57161 |
|---|---|
| M. Wt | 334.37 |
| Formula | C19H18N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2987586-62-7 |
| Synonyms | |
| SMILES | O=C1C2=NC3=C(C(N2C4=C1C(NCCN(C)C)=CC=C4)=O)C=CC=C3 |
Biological Activity
| Description | Topoisomerase II inhibitor 6 is a potent and selective inhibitor of topoisomerase II, derived from tryptanthrin. This compound demonstrates significant antiproliferative activity across various tumor cell lines and effectively halts the cell cycle of CCRF-CEM cells at the G2 phase, while inducing DNA double-strand breaks (DSBs). Its robust mechanism of action makes Topoisomerase II inhibitor 6 a valuable reagent for cancer research and therapeutic investigations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
