Product Data Sheet
Salvicine
Catalog No. A57173
Salvicine is a potent inhibitor of DNA topoisomerase II, exhibiting an IC50 of 3 μM. By targeting the ATPase domain of Topo II, Salvicine enhances its interaction with DNA, thereby inhibiting DNA degradation and ATP hydrolysis. This compound demonstrates significant anticancer properties, including the induction of DNA damage, the potential to overcome multidrug resistance, and the inhibition of tumor cell adhesion, making it a valuable tool for cancer research applications.
Chemical Information
| Catalog Num | A57173 |
|---|---|
| M. Wt | 330.42 |
| Formula | C20H26O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 240423-23-8 |
| Synonyms | |
| SMILES | O=C1C(C(C(C)C)=CC2=C1C(CCC(C(C)(C)O)O)=C(C)C=C2)=O |
Biological Activity
| Description | Salvicine is a potent inhibitor of DNA topoisomerase II, exhibiting an IC50 of 3 μM. By targeting the ATPase domain of Topo II, Salvicine enhances its interaction with DNA, thereby inhibiting DNA degradation and ATP hydrolysis. This compound demonstrates significant anticancer properties, including the induction of DNA damage, the potential to overcome multidrug resistance, and the inhibition of tumor cell adhesion, making it a valuable tool for cancer research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
