Product Data Sheet
Topoisomerase IIα-IN-1
Catalog No. A57179
Topoisomerase IIα-IN-1 is a selective inhibitor of topoisomerase IIα, a key enzyme involved in DNA strand separation and replication. This compound demonstrates significant antiproliferative activity against various human cancer cell lines, making it a valuable tool for cancer research. Its ability to disrupt DNA topology positions Topoisomerase IIα-IN-1 as a promising candidate for studies focused on tumorigenesis and therapeutic interventions in oncology.
Chemical Information
| Catalog Num | A57179 |
|---|---|
| M. Wt | 420.42 |
| Formula | C22H20N4O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2407521-87-1 |
| Synonyms | |
| SMILES | O=C1C2=NC=CC=C2C(C(OC3=C4)=C1)=NC3=CC=C4C(N[C@H](C(O)=O)CCCCN)=O |
Biological Activity
| Description | Topoisomerase IIα-IN-1 is a selective inhibitor of topoisomerase IIα, a key enzyme involved in DNA strand separation and replication. This compound demonstrates significant antiproliferative activity against various human cancer cell lines, making it a valuable tool for cancer research. Its ability to disrupt DNA topology positions Topoisomerase IIα-IN-1 as a promising candidate for studies focused on tumorigenesis and therapeutic interventions in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
