Product Data Sheet
Indimitecan hydrochloride
Catalog No. A57184
Indimitecan hydrochloride is a potent inhibitor of topoisomerase I (Top1), a key enzyme involved in DNA replication and repair. This compound exhibits significant anticancer activity by inducing DNA damage and inhibiting cellular proliferation in tumor cells. Indimitecan hydrochloride is utilized in cancer research to study mechanisms of drug action and to evaluate therapeutic strategies targeting Top1.
Chemical Information
| Catalog Num | A57184 |
|---|---|
| M. Wt | 495.91 |
| Formula | C25H22ClN3O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 915303-04-7 |
| Synonyms | LMP776 hydrochloride |
| SMILES | O=C1C2=C(C3=C1C4=CC(OC)=C(C=C4C(N3CCCN5C=NC=C5)=O)OC)C=C6OCOC6=C2.Cl |
Biological Activity
| Description | Indimitecan hydrochloride is a potent inhibitor of topoisomerase I (Top1), a key enzyme involved in DNA replication and repair. This compound exhibits significant anticancer activity by inducing DNA damage and inhibiting cellular proliferation in tumor cells. Indimitecan hydrochloride is utilized in cancer research to study mechanisms of drug action and to evaluate therapeutic strategies targeting Top1. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
