Intoplicine dimesylate
Catalog No. A57194

Intoplicine dimesylate is a potent inhibitor of DNA topoisomerase I and II. This compound, a derivative of the 7H-benzo[e]pyrido[4,3-b]indole series, exerts its antitumor effects by strongly binding to DNA, resulting in an increased length of linear DNA. Intoplicine dimesylate is useful in cancer research and studies involving DNA topology.
Chemical Information
| Catalog Num | A57194 |
|---|---|
| M. Wt | 540.65 |
| Formula | C23H32N4O7S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 133711-99-6 |
| Synonyms | RP 60475 dimesylate |
| SMILES | OC1=CC=C2C3=C(NC4=C3C(NCCCN(C)C)=NC=C4C)C=CC2=C1.CS(O)(=O)=O.CS(O)(=O)=O |
Biological Activity
| Description | Intoplicine dimesylate is a potent inhibitor of DNA topoisomerase I and II. This compound, a derivative of the 7H-benzo[e]pyrido[4,3-b]indole series, exerts its antitumor effects by strongly binding to DNA, resulting in an increased length of linear DNA. Intoplicine dimesylate is useful in cancer research and studies involving DNA topology. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


