Product Data Sheet

WEE1-IN-4

Catalog No. A57241

main product photo
WEE1-IN-4 is a potent inhibitor of the Wee1 kinase, exhibiting an IC50 of 0.011 μM. By targeting and inhibiting Wee1, this compound effectively abrogates the G2/M checkpoint, thereby promoting cell cycle progression in cancer cells. WEE1-IN-4 serves as a valuable tool for research in cancer biology and therapeutics, particularly in studies focused on cell cycle regulation and the development of combination therapies.
Chemical Information
Catalog NumA57241
M. Wt362.77
FormulaC20H11ClN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.622855-37-2
Synonyms
SMILESO=C1NC(C2=C1C3=C(C=C2C4=CC=CC=C4Cl)NC5=C3C=C(O)C=C5)=O
Biological Activity
DescriptionWEE1-IN-4 is a potent inhibitor of the Wee1 kinase, exhibiting an IC50 of 0.011 μM. By targeting and inhibiting Wee1, this compound effectively abrogates the G2/M checkpoint, thereby promoting cell cycle progression in cancer cells. WEE1-IN-4 serves as a valuable tool for research in cancer biology and therapeutics, particularly in studies focused on cell cycle regulation and the development of combination therapies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.