Product Data Sheet
Adavosertib-C3-NH-Boc
Catalog No. A57266
Adavosertib-C3-NH-Boc is a target protein ligand-linker conjugate designed to incorporate a Wee1 ligand and a PROTAC linker, facilitating the recruitment of E3 ligases. This compound enables the synthesis of PROTAC Pomalidomide-C3-adavosertib, allowing for targeted protein degradation studies. It serves as a useful tool in the exploration of therapeutic mechanisms involving protein regulation and degradation in cancer research and other biological applications.
Chemical Information
| Catalog Num | A57266 |
|---|---|
| M. Wt | 643.78 |
| Formula | C34H45N9O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2113725-19-0 |
| Synonyms | |
| SMILES | O=C1N(CC=C)N(C2=NC(C(O)(C)C)=CC=C2)C3=NC(NC4=CC=C(N5CCN(CCCNC(OC(C)(C)C)=O)CC5)C=C4)=NC=C31 |
Biological Activity
| Description | Adavosertib-C3-NH-Boc is a target protein ligand-linker conjugate designed to incorporate a Wee1 ligand and a PROTAC linker, facilitating the recruitment of E3 ligases. This compound enables the synthesis of PROTAC Pomalidomide-C3-adavosertib, allowing for targeted protein degradation studies. It serves as a useful tool in the exploration of therapeutic mechanisms involving protein regulation and degradation in cancer research and other biological applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
