Product Data Sheet
Drp1 peptide inhibitor P110
Catalog No. A57363
Drp1 peptide inhibitor P110 is a selective inhibitor of Dynamin-related protein 1 (Drp1), targeting mitochondrial dynamics. This compound exhibits neuroprotective effects by inhibiting Drp1 activation, preventing MPTP-induced mitochondrial translocation, and mitigating dopaminergic neuron loss along with associated behavioral deficits. Research applications include studies on Alzheimer's disease, as well as models of Huntington's disease, cerebral ischemic injury, and myocardial infarction, where P110 has demonstrated the ability to reduce mitochondrial damage and alleviate organ injury.
Chemical Information
| Catalog Num | A57363 |
|---|---|
| M. Wt | 2411.78 |
| Formula | C100H179N45O25 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2770267-63-3 |
| Synonyms | |
| SMILES | C([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC1=CC=C(O)C=C1)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)=O)CC(O)=O)=O)CC(C)C)=O)CC(C)C)(=O)N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N)=O)CO)=O)=O)CCCNC(=N)N)=O)CCC2 |
Biological Activity
| Description | Drp1 peptide inhibitor P110 is a selective inhibitor of Dynamin-related protein 1 (Drp1), targeting mitochondrial dynamics. This compound exhibits neuroprotective effects by inhibiting Drp1 activation, preventing MPTP-induced mitochondrial translocation, and mitigating dopaminergic neuron loss along with associated behavioral deficits. Research applications include studies on Alzheimer's disease, as well as models of Huntington's disease, cerebral ischemic injury, and myocardial infarction, where P110 has demonstrated the ability to reduce mitochondrial damage and alleviate organ injury. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
