Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
Catalog No. A57449

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) functions as an inhibitory peptide targeting the α5β1 integrin. This synthetic ligand effectively competes with invasin for binding to the α5β1 integrin on Caco-2 cells, thereby disrupting cell adhesion and signaling processes. Its application is significant in studying integrin-related interactions and cellular behaviors, making it a valuable tool in cancer and cell biology research.
Chemical Information
| Catalog Num | A57449 |
|---|---|
| M. Wt | 569.57 |
| Formula | C22H35N9O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 135432-37-0 |
| Synonyms | c(GRGDSP) |
| SMILES |
Biological Activity
| Description | Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) functions as an inhibitory peptide targeting the α5β1 integrin. This synthetic ligand effectively competes with invasin for binding to the α5β1 integrin on Caco-2 cells, thereby disrupting cell adhesion and signaling processes. Its application is significant in studying integrin-related interactions and cellular behaviors, making it a valuable tool in cancer and cell biology research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


