Product Data Sheet

α4β7 Integrin-IN-2

Catalog No. A57456

main product photo
α4β7 Integrin-IN-2 is a potent antagonist of human α4β7 integrin, demonstrating an IC50 of less than 5 nM. This compound effectively modulates α4β7 integrin-mediated biological pathways, making it a valuable tool for investigating inflammatory diseases. Its strong inhibitory activity positions it for use in research aimed at understanding mechanisms of inflammation and potential therapeutic interventions.
Chemical Information
Catalog NumA57456
M. Wt649.69
FormulaC34H40F5N3O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2640360-68-3
Synonyms
SMILESCC1=C(C(C)=CC(F)=C1)C2=CC([C@H](CC(O)=O)NC([C@@H](N3C=C(C(C(F)(F)F)=CC3=O)CCN(C)C)CC(C)C)=O)=C(C(C)=C2)F
Biological Activity
Descriptionα4β7 Integrin-IN-2 is a potent antagonist of human α4β7 integrin, demonstrating an IC50 of less than 5 nM. This compound effectively modulates α4β7 integrin-mediated biological pathways, making it a valuable tool for investigating inflammatory diseases. Its strong inhibitory activity positions it for use in research aimed at understanding mechanisms of inflammation and potential therapeutic interventions.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.