Product Data Sheet
FNIII14
Catalog No. A57466
FNIII14 is an anti-adhesive peptide derived from the 14th fibronectin type III repeat. It effectively inhibits cell adhesion to the extracellular matrix by inducing a conformational change in β1-integrin, shifting it from an active to an inactive state and blocking integrin-mediated signaling. FNIII14 demonstrates anti-fibrotic and anti-cancer properties, making it a valuable tool for research in areas such as metabolic diseases, organ fibrosis, and malignant tumors.
Chemical Information
| Catalog Num | A57466 |
|---|---|
| M. Wt | 2255.52 |
| Formula | C103H163N21O35 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 206536-96-1 |
| Synonyms | |
| SMILES | C([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCC(O)=O)=O)C)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)=O)CC(C)C)=O)CCC(O)=O)(=O)N1[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)[C@H](CC)C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)=O)CCC1 |
Biological Activity
| Description | FNIII14 is an anti-adhesive peptide derived from the 14th fibronectin type III repeat. It effectively inhibits cell adhesion to the extracellular matrix by inducing a conformational change in β1-integrin, shifting it from an active to an inactive state and blocking integrin-mediated signaling. FNIII14 demonstrates anti-fibrotic and anti-cancer properties, making it a valuable tool for research in areas such as metabolic diseases, organ fibrosis, and malignant tumors. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
