Product Data Sheet
α4β7 Integrin-IN-1
Catalog No. A57468
α4β7 Integrin-IN-1 is a highly effective inhibitor of the α4β7 integrin, specifically blocking its interaction with MadCAM-1 with an EC50 value of 0.05 nM. This compound is primarily utilized in research applications related to inflammatory bowel disease, providing insights into therapeutic strategies targeting integrin-mediated pathways. Its high potency makes it a valuable tool for studying cell adhesion processes and related inflammatory mechanisms.
Chemical Information
| Catalog Num | A57468 |
|---|---|
| M. Wt | 680.61 |
| Formula | C33H28F4N6O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2417307-52-7 |
| Synonyms | |
| SMILES | CN(C(N1C2=CC=C(C3=C2N=CC=C3)C[C@H](NC(C(C(F)=C4)=C(C)C=C4N5CCOC[C@@H]5C(F)(F)F)=O)C(O)=O)=O)C6=CN=CC=C6C1=O |
Biological Activity
| Description | α4β7 Integrin-IN-1 is a highly effective inhibitor of the α4β7 integrin, specifically blocking its interaction with MadCAM-1 with an EC50 value of 0.05 nM. This compound is primarily utilized in research applications related to inflammatory bowel disease, providing insights into therapeutic strategies targeting integrin-mediated pathways. Its high potency makes it a valuable tool for studying cell adhesion processes and related inflammatory mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
