Product Data Sheet
CP-664511
Catalog No. A57488
CP-664511 is a potent α4β1 integrin antagonist with an IC50 of 0.52 nM, exhibiting significant anti-inflammatory properties. By inhibiting the interaction between α4β1 integrin and vascular cell adhesion molecule-1 (VCAM-1), CP-664511 effectively reduces eosinophil infiltration into lung tissue. This compound is valuable for investigating mechanisms underlying asthma and allergic airway diseases.
Chemical Information
| Catalog Num | A57488 |
|---|---|
| M. Wt | 522.59 |
| Formula | C28H34N4O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 379692-00-9 |
| Synonyms | |
| SMILES | O=C(O)CCC1=CC([C@@H](NC(CC2=CC=C(NC(NC3=CC=CC=C3C)=O)C(OC)=C2)=O)CC(C)C)=NO1 |
Biological Activity
| Description | CP-664511 is a potent α4β1 integrin antagonist with an IC50 of 0.52 nM, exhibiting significant anti-inflammatory properties. By inhibiting the interaction between α4β1 integrin and vascular cell adhesion molecule-1 (VCAM-1), CP-664511 effectively reduces eosinophil infiltration into lung tissue. This compound is valuable for investigating mechanisms underlying asthma and allergic airway diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
