Product Data Sheet

MOTS-c (mouse)

Catalog No. A57633

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MOTS-c (mouse) is a mitochondrial-derived polypeptide that acts as an AMPK activator. It has been shown to modulate pancreatic cell function by reducing insulin secretion and expression in INS-1E cells, while enhancing glucagon secretion in αTC-1 cells. Additionally, MOTS-c (mouse) is effective in decreasing apoptosis in both INS-1E and αTC-1 cell lines. Its ability to counteract diet-induced obesity and insulin resistance highlights its potential in metabolic research.
Chemical Information
Catalog NumA57633
M. Wt1446.73
FormulaC69H99N13O17S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2209854-03-3
Synonyms
SMILES
Biological Activity
DescriptionMOTS-c (mouse) is a mitochondrial-derived polypeptide that acts as an AMPK activator. It has been shown to modulate pancreatic cell function by reducing insulin secretion and expression in INS-1E cells, while enhancing glucagon secretion in αTC-1 cells. Additionally, MOTS-c (mouse) is effective in decreasing apoptosis in both INS-1E and αTC-1 cell lines. Its ability to counteract diet-induced obesity and insulin resistance highlights its potential in metabolic research.
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