Product Data Sheet
ALKBH1-IN-3 prodrug
Catalog No. A57647
ALKBH1-IN-3 prodrug is a potent inhibitor of the DNA N6-methyladenine demethylase ALKBH1, functioning primarily through modulation of the AMPK signaling pathway. This prodrug significantly enhances the cellular abundance of 6mA, leading to a reduction in the viability of gastric cancer cells. With its strong cellular activity and favorable in vivo metabolic profile, ALKBH1-IN-3 prodrug is a valuable tool for investigating mechanisms underlying gastric cancer and the role of epigenetic modifications in tumor biology.
Chemical Information
| Catalog Num | A57647 |
|---|---|
| M. Wt | 354.36 |
| Formula | C18H18N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3056005-98-9 |
| Synonyms | |
| SMILES | O=C(C1=CN(C2=NC=C(C=N2)OCC3=CC(OC)=CC=C3)N=C1)OCC |
Biological Activity
| Description | ALKBH1-IN-3 prodrug is a potent inhibitor of the DNA N6-methyladenine demethylase ALKBH1, functioning primarily through modulation of the AMPK signaling pathway. This prodrug significantly enhances the cellular abundance of 6mA, leading to a reduction in the viability of gastric cancer cells. With its strong cellular activity and favorable in vivo metabolic profile, ALKBH1-IN-3 prodrug is a valuable tool for investigating mechanisms underlying gastric cancer and the role of epigenetic modifications in tumor biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
